ANGSD: Analysis of next generation Sequencing Data

Latest tar.gz version is (0.938/0.939 on github), see Change_log for changes, and download it here.

Change log

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Revision as of 18:07, 18 June 2012 by Albrecht (talk | contribs) (Created page with "=Version notes= * 0.16 Is now bundled with SAMtools-0.1.17 and the mpileup (and friends) command be used for passing data to dirty. * 0.17 added extra options -minInd and -min...")
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Version notes

  • 0.16 Is now bundled with SAMtools-0.1.17 and the mpileup (and friends) command be used for passing data to dirty.
  • 0.17 added extra options -minInd and -minMaf, for only printing and using sites above a threshold
  • 0.18 added option to pass reference and ancestral allele as fasta files.(using faidx format) (doMaf is now encoded internally as a MAF_(UN)KNOWN_TYPE)
  • 0.19 added support for tglf inputfiles, -tglf -posfile see runexamples, also added the likeratio test for snp calling
  • 0.20 Added the check for missing data, before the major/minor. included -realSFS, changed the deallocation of the -doMAF results, such that its proper cleaned up.
  • 0.21 refactored pml.cpp into pml_estError_genLikes.cpp and pml_freq_asso.cpp (fixed a bug that preventede -samglf and samglfclean from working)
  • 0.22 Well this update was a mixture of edits from user:albrecht and BGI so its difficult to give a concise description
  • .0.23 Program can now read simulated files (single pop only) An example can be seen in "full example ... sfs" and input types.
  • 0.24 added the tajima estimator. This should go in tandem with some R scripts. Had to modify parseargs, shared, and pml_freq_asso
  • 0.25 the depth is now being populated when using mpileup -g. The program can now get the counts from mpileup

ANGSD below

  • 0.01.a - 0.01.b The bfgs now supports threading, maybe anders implemented a heteorzygosity estimator.
  • 0.01.c A problem if we didn't observe any llh, caused the MAF estimator to 'nan'.
  • 0.02 Fixed small bug in bfgs optimization of sfs optimization. When choosing a region bigger than what was covered by the .sfs file the program would hang. Added genotypecaller, added -sfsEst to the realSFS part of the program.
  • 0.03 added and documented genotypecaller, can dump counts,-realSFS 1 dumps positions, -realSFS 2 is deprecated,S,pi and tajima has been added to sfstools along with possibility to do prior