Anders Albrechtsen Publications

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Ryan K Waples, Anders Albrechtsen, Ida Moltke
Allele frequency-free inference of close familial relationships from genotypes or low depth sequencing data.
Mol. Ecol.: 2018;
[PubMed:30462358] (I a)

Siyang Liu, Shujia Huang, Fang Chen, Lijian Zhao, Yuying Yuan, Stephen Starko Francis, Lin Fang, Zilong Li, Long Lin, Rong Liu, Yong Zhang, Huixin Xu, Shengkang Li, Yuwen Zhou, Robert W Davies, Qiang Liu, Robin G Walters, Kuang Lin, Jia Ju, Thorfinn Korneliussen, Melinda A Yang, Qiaomei Fu, Jun Wang, Lijun Zhou, Anders Krogh, Hongyun Zhang, Wei Wang, Zhengming Chen, Zhiming Cai, Ye Yin, Huanming Yang, Mao Mao, Jay Shendure, Jian Wang, Anders Albrechtsen, Xin Jin, Rasmus Nielsen, Xun Xu
Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History.
Cell: 2018, 175(2);347-359.e14
[PubMed:30290141] (I p)

Jonas Meisner, Anders Albrechtsen
Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data.
Genetics: 2018, 210(2);719-731
[PubMed:30131346] (I p)

Niels Grarup, Ida Moltke, Mette K Andersen, Peter Bjerregaard, Christina V L Larsen, Inger K Dahl-Petersen, Emil Jørsboe, Hemant K Tiwari, Scarlett E Hopkins, Howard W Wiener, Bert B Boyer, Allan Linneberg, Oluf Pedersen, Marit E Jørgensen, Anders Albrechtsen, Torben Hansen
Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population.
Diabetologia: 2018;
[PubMed:29926116] (I a)

Mette Korre Andersen, Niels Grarup, Ida Moltke, Anders Albrechtsen, Torben Hansen
Genetic architecture of obesity and related metabolic traits-recent insights from isolated populations.
Curr. Opin. Genet. Dev.: 2018, 50;74-78
[PubMed:29510341] (I p)

Emil V R Appel, Ida Moltke, Marit E Jørgensen, Peter Bjerregaard, Allan Linneberg, Oluf Pedersen, Anders Albrechtsen, Torben Hansen, Niels Grarup
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population.
Eur. J. Hum. Genet.: 2018, 26(6);868-875
[PubMed:29483669] (I p)

Charleen Gaunitz, Antoine Fages, Kristian Hanghøj, Anders Albrechtsen, Naveed Khan, Mikkel Schubert, Andaine Seguin-Orlando, Ivy J Owens, Sabine Felkel, Olivier Bignon-Lau, Peter de Barros Damgaard, Alissa Mittnik, Azadeh F Mohaseb, Hossein Davoudi, Saleh Alquraishi, Ahmed H Alfarhan, Khaled A S Al-Rasheid, Eric Crubézy, Norbert Benecke, Sandra Olsen, Dorcas Brown, David Anthony, Ken Massy, Vladimir Pitulko, Aleksei Kasparov, Gottfried Brem, Michael Hofreiter, Gulmira Mukhtarova, Nurbol Baimukhanov, Lembi Lõugas, Vedat Onar, Philipp W Stockhammer, Johannes Krause, Bazartseren Boldgiv, Sainbileg Undrakhbold, Diimaajav Erdenebaatar, Sébastien Lepetz, Marjan Mashkour, Arne Ludwig, Barbara Wallner, Victor Merz, Ilja Merz, Viktor Zaibert, Eske Willerslev, Pablo Librado, Alan K Outram, Ludovic Orlando
Ancient genomes revisit the ancestry of domestic and Przewalski's horses.
Science: 2018, 360(6384);111-114
[PubMed:29472442] (I p)

Casper-Emil T Pedersen, Anders Albrechtsen, Paul D Etter, Eric A Johnson, Ludovic Orlando, Lounes Chikhi, Hans R Siegismund, Rasmus Heller
A southern African origin and cryptic structure in the highly mobile plains zebra.
Nat Ecol Evol: 2018, 2(3);491-498
[PubMed:29358610] (I p)

J Víctor Moreno-Mayar, Ben A Potter, Lasse Vinner, Matthias Steinrücken, Simon Rasmussen, Jonathan Terhorst, John A Kamm, Anders Albrechtsen, Anna-Sapfo Malaspinas, Martin Sikora, Joshua D Reuther, Joel D Irish, Ripan S Malhi, Ludovic Orlando, Yun S Song, Rasmus Nielsen, David J Meltzer, Eske Willerslev
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.
Nature: 2018, 553(7687);203-207
[PubMed:29323294] (I p)

Niels Grarup, Ida Moltke, Mette K Andersen, Maria Dalby, Kristoffer Vitting-Seerup, Timo Kern, Yuvaraj Mahendran, Emil Jørsboe, Christina V L Larsen, Inger K Dahl-Petersen, Arthur Gilly, Daniel Suveges, George Dedoussis, Eleftheria Zeggini, Oluf Pedersen, Robin Andersson, Peter Bjerregaard, Marit E Jørgensen, Anders Albrechtsen, Torben Hansen
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes.
Nat. Genet.: 2018, 50(2);172-174
[PubMed:29311636] (I p)

Samuele Soraggi, Carsten Wiuf, Anders Albrechtsen
Powerful Inference with the D-Statistic on Low-Coverage Whole-Genome Data.
G3 (Bethesda): 2018, 8(2);551-566
[PubMed:29196497] (I e)

Jes Sloth Mathiesen, Jens Peter Kroustrup, Peter Vestergaard, Kirstine Stochholm, Per Løgstrup Poulsen, Åse Krogh Rasmussen, Ulla Feldt-Rasmussen, Mette Gaustadnes, Torben Falck Ørntoft, Maria Rossing, Finn Cilius Nielsen, Anders Albrechtsen, Kim Brixen, Christian Godballe, Anja Lisbeth Frederiksen

Thyroid: 2017, 27(12);1505-1510
[PubMed:29020875] (I p)

Martin Sikora, Andaine Seguin-Orlando, Vitor C Sousa, Anders Albrechtsen, Thorfinn Korneliussen, Amy Ko, Simon Rasmussen, Isabelle Dupanloup, Philip R Nigst, Marjolein D Bosch, Gabriel Renaud, Morten E Allentoft, Ashot Margaryan, Sergey V Vasilyev, Elizaveta V Veselovskaya, Svetlana B Borutskaya, Thibaut Deviese, Dan Comeskey, Tom Higham, Andrea Manica, Robert Foley, David J Meltzer, Rasmus Nielsen, Laurent Excoffier, Marta Mirazon Lahr, Ludovic Orlando, Eske Willerslev
Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers.
Science: 2017, 358(6363);659-662
[PubMed:28982795] (I p)

Emil Jørsboe, Kristian Hanghøj, Anders Albrechtsen
fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample.
Bioinformatics: 2017, 33(19);3148-3150
[PubMed:28957500] (I p)

Pablo Librado, Cristina Gamba, Charleen Gaunitz, Clio Der Sarkissian, Mélanie Pruvost, Anders Albrechtsen, Antoine Fages, Naveed Khan, Mikkel Schubert, Vidhya Jagannathan, Aitor Serres-Armero, Lukas F K Kuderna, Inna S Povolotskaya, Andaine Seguin-Orlando, Sébastien Lepetz, Markus Neuditschko, Catherine Thèves, Saleh Alquraishi, Ahmed H Alfarhan, Khaled Al-Rasheid, Stefan Rieder, Zainolla Samashev, Henri-Paul Francfort, Norbert Benecke, Michael Hofreiter, Arne Ludwig, Christine Keyser, Tomas Marques-Bonet, Bertrand Ludes, Eric Crubézy, Tosso Leeb, Eske Willerslev, Ludovic Orlando
Ancient genomic changes associated with domestication of the horse.
Science: 2017, 356(6336);442-445
[PubMed:28450643] (I p)

Fernando Racimo, David Gokhman, Matteo Fumagalli, Amy Ko, Torben Hansen, Ida Moltke, Anders Albrechtsen, Liran Carmel, Emilia Huerta-Sánchez, Rasmus Nielsen
Archaic Adaptive Introgression in TBX15/WARS2.
Mol. Biol. Evol.: 2017, 34(3);509-524
[PubMed:28007980] (I p)

Casper-Emil T Pedersen, Kirk E Lohmueller, Niels Grarup, Peter Bjerregaard, Torben Hansen, Hans R Siegismund, Ida Moltke, Anders Albrechtsen
The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit.
Genetics: 2017, 205(2);787-801
[PubMed:27903613] (I p)

Maria Rossing, Anders Albrechtsen, Anne-Bine Skytte, Uffe B Jensen, Lilian B Ousager, Anne-Marie Gerdes, Finn C Nielsen, Thomas vO Hansen
Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation.
J. Hum. Genet.: 2017, 62(2);151-157
[PubMed:27734835] (I p)

Anna-Sapfo Malaspinas, Michael C Westaway, Craig Muller, Vitor C Sousa, Oscar Lao, Isabel Alves, Anders Bergström, Georgios Athanasiadis, Jade Y Cheng, Jacob E Crawford, Tim H Heupink, Enrico Macholdt, Stephan Peischl, Simon Rasmussen, Stephan Schiffels, Sankar Subramanian, Joanne L Wright, Anders Albrechtsen, Chiara Barbieri, Isabelle Dupanloup, Anders Eriksson, Ashot Margaryan, Ida Moltke, Irina Pugach, Thorfinn S Korneliussen, Ivan P Levkivskyi, J Víctor Moreno-Mayar, Shengyu Ni, Fernando Racimo, Martin Sikora, Yali Xue, Farhang A Aghakhanian, Nicolas Brucato, Søren Brunak, Paula F Campos, Warren Clark, Sturla Ellingvåg, Gudjugudju Fourmile, Pascale Gerbault, Darren Injie, George Koki, Matthew Leavesley, Betty Logan, Aubrey Lynch, Elizabeth A Matisoo-Smith, Peter J McAllister, Alexander J Mentzer, Mait Metspalu, Andrea B Migliano, Les Murgha, Maude E Phipps, William Pomat, Doc Reynolds, Francois-Xavier Ricaut, Peter Siba, Mark G Thomas, Thomas Wales, Colleen Ma'run Wall, Stephen J Oppenheimer, Chris Tyler-Smith, Richard Durbin, Joe Dortch, Andrea Manica, Mikkel H Schierup, Robert A Foley, Marta Mirazón Lahr, Claire Bowern, Jeffrey D Wall, Thomas Mailund, Mark Stoneking, Rasmus Nielsen, Manjinder S Sandhu, Laurent Excoffier, David M Lambert, Eske Willerslev
A genomic history of Aboriginal Australia.
Nature: 2016, 538(7624);207-214
[PubMed:27654914] (I p)

Mette Korre Andersen, Emil Jørsboe, Camilla Helene Sandholt, Niels Grarup, Marit Eika Jørgensen, Nils Joakim Færgeman, Peter Bjerregaard, Oluf Pedersen, Ida Moltke, Torben Hansen, Anders Albrechtsen
Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders.
PLoS Genet.: 2016, 12(6);e1006119
[PubMed:27341449] (I e)

Mette Korre Andersen, Casper-Emil Tingskov Pedersen, Ida Moltke, Torben Hansen, Anders Albrechtsen, Niels Grarup
Genetics of Type 2 Diabetes: the Power of Isolated Populations.
Curr. Diab. Rep.: 2016, 16(7);65
[PubMed:27189761] (I p)

Rute R da Fonseca, Anders Albrechtsen, Gonçalo Espregueira Themudo, Jazmín Ramos-Madrigal, Jonas Andreas Sibbesen, Lasse Maretty, M Lisandra Zepeda-Mendoza, Paula F Campos, Rasmus Heller, Ricardo J Pereira
Next-generation biology: Sequencing and data analysis approaches for non-model organisms.
Mar Genomics: 2016, 30;3-13
[PubMed:27184710] (I p)

Filipe G Vieira, Anders Albrechtsen, Rasmus Nielsen
Estimating IBD tracts from low coverage NGS data.
Bioinformatics: 2016, 32(14);2096-102
[PubMed:27153648] (I p)

Niels Grarup, Ida Moltke, Anders Albrechtsen, Torben Hansen
Diabetes in Population Isolates: Lessons from Greenland.
Rev Diabet Stud: 2016, 12(3-4);320-9
[PubMed:27111118] (I p)

Gardar Sveinbjornsson, Anders Albrechtsen, Florian Zink, Sigurjón A Gudjonsson, Asmundur Oddson, Gísli Másson, Hilma Holm, Augustine Kong, Unnur Thorsteinsdottir, Patrick Sulem, Daniel F Gudbjartsson, Kari Stefansson
Weighting sequence variants based on their annotation increases power of whole-genome association studies.
Nat. Genet.: 2016, 48(3);314-7
[PubMed:26854916] (I p)

Pablo Librado, Clio Der Sarkissian, Luca Ermini, Mikkel Schubert, Hákon Jónsson, Anders Albrechtsen, Matteo Fumagalli, Melinda A Yang, Cristina Gamba, Andaine Seguin-Orlando, Cecilie D Mortensen, Bent Petersen, Cindi A Hoover, Belen Lorente-Galdos, Artem Nedoluzhko, Eugenia Boulygina, Svetlana Tsygankova, Markus Neuditschko, Vidhya Jagannathan, Catherine Thèves, Ahmed H Alfarhan, Saleh A Alquraishi, Khaled A S Al-Rasheid, Thomas Sicheritz-Ponten, Ruslan Popov, Semyon Grigoriev, Anatoly N Alekseev, Edward M Rubin, Molly McCue, Stefan Rieder, Tosso Leeb, Alexei Tikhonov, Eric Crubézy, Montgomery Slatkin, Tomas Marques-Bonet, Rasmus Nielsen, Eske Willerslev, Juha Kantanen, Egor Prokhortchouk, Ludovic Orlando
Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environments.
Proc. Natl. Acad. Sci. U.S.A.: 2015, 112(50);E6889-97
[PubMed:26598656] (I p)

Shzeena Dad, Nanna D Rendtorff, Erik Kann, Anders Albrechtsen, Mana M Mehrjouy, Mads Bak, Niels Tommerup, Lisbeth Tranebjærg, Thomas Rosenberg, Hanne Jensen, Lisbeth B Møller
Partial USH2A deletions contribute to Usher syndrome in Denmark.
Eur. J. Hum. Genet.: 2015, 23(12);1750
[PubMed:26559128] (I p)

Clio Der Sarkissian, Luca Ermini, Mikkel Schubert, Melinda A Yang, Pablo Librado, Matteo Fumagalli, Hákon Jónsson, Gila Kahila Bar-Gal, Anders Albrechtsen, Filipe G Vieira, Bent Petersen, Aurélien Ginolhac, Andaine Seguin-Orlando, Kim Magnussen, Antoine Fages, Cristina Gamba, Belen Lorente-Galdos, Sagi Polani, Cynthia Steiner, Markus Neuditschko, Vidhya Jagannathan, Claudia Feh, Charles L Greenblatt, Arne Ludwig, Natalia I Abramson, Waltraut Zimmermann, Renate Schafberg, Alexei Tikhonov, Thomas Sicheritz-Ponten, Eske Willerslev, Tomas Marques-Bonet, Oliver A Ryder, Molly McCue, Stefan Rieder, Tosso Leeb, Montgomery Slatkin, Ludovic Orlando
Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse.
Curr. Biol.: 2015, 25(19);2577-83
[PubMed:26412128] (I p)

Matteo Fumagalli, Ida Moltke, Niels Grarup, Fernando Racimo, Peter Bjerregaard, Marit E Jørgensen, Thorfinn S Korneliussen, Pascale Gerbault, Line Skotte, Allan Linneberg, Cramer Christensen, Ivan Brandslund, Torben Jørgensen, Emilia Huerta-Sánchez, Erik B Schmidt, Oluf Pedersen, Torben Hansen, Anders Albrechtsen, Rasmus Nielsen
Greenlandic Inuit show genetic signatures of diet and climate adaptation.
Science: 2015, 349(6254);1343-7
[PubMed:26383953] (I p)

Maanasa Raghavan, Matthias Steinrücken, Kelley Harris, Stephan Schiffels, Simon Rasmussen, Michael DeGiorgio, Anders Albrechtsen, Cristina Valdiosera, María C Ávila-Arcos, Anna-Sapfo Malaspinas, Anders Eriksson, Ida Moltke, Mait Metspalu, Julian R Homburger, Jeff Wall, Omar E Cornejo, J Víctor Moreno-Mayar, Thorfinn S Korneliussen, Tracey Pierre, Morten Rasmussen, Paula F Campos, Peter de Barros Damgaard, Morten E Allentoft, John Lindo, Ene Metspalu, Ricardo Rodríguez-Varela, Josefina Mansilla, Celeste Henrickson, Andaine Seguin-Orlando, Helena Malmström, Thomas Stafford, Suyash S Shringarpure, Andrés Moreno-Estrada, Monika Karmin, Kristiina Tambets, Anders Bergström, Yali Xue, Vera Warmuth, Andrew D Friend, Joy Singarayer, Paul Valdes, Francois Balloux, Ilán Leboreiro, Jose Luis Vera, Hector Rangel-Villalobos, Davide Pettener, Donata Luiselli, Loren G Davis, Evelyne Heyer, Christoph P E Zollikofer, Marcia S Ponce de León, Colin I Smith, Vaughan Grimes, Kelly-Anne Pike, Michael Deal, Benjamin T Fuller, Bernardo Arriaza, Vivien Standen, Maria F Luz, Francois Ricaut, Niede Guidon, Ludmila Osipova, Mikhail I Voevoda, Olga L Posukh, Oleg Balanovsky, Maria Lavryashina, Yuri Bogunov, Elza Khusnutdinova, Marina Gubina, Elena Balanovska, Sardana Fedorova, Sergey Litvinov, Boris Malyarchuk, Miroslava Derenko, M J Mosher, David Archer, Jerome Cybulski, Barbara Petzelt, Joycelynn Mitchell, Rosita Worl, Paul J Norman, Peter Parham, Brian M Kemp, Toomas Kivisild, Chris Tyler-Smith, Manjinder S Sandhu, Michael Crawford, Richard Villems, David Glenn Smith, Michael R Waters, Ted Goebel, John R Johnson, Ripan S Malhi, Mattias Jakobsson, David J Meltzer, Andrea Manica, Richard Durbin, Carlos D Bustamante, Yun S Song, Rasmus Nielsen, Eske Willerslev
POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.
Science: 2015, 349(6250);aab3884
[PubMed:26198033] (I p)

Morten Rasmussen, Martin Sikora, Anders Albrechtsen, Thorfinn Sand Korneliussen, J Víctor Moreno-Mayar, G David Poznik, Christoph P E Zollikofer, Marcia Ponce de León, Morten E Allentoft, Ida Moltke, Hákon Jónsson, Cristina Valdiosera, Ripan S Malhi, Ludovic Orlando, Carlos D Bustamante, Thomas W Stafford, David J Meltzer, Rasmus Nielsen, Eske Willerslev
The ancestry and affiliations of Kennewick Man.
Nature: 2015, 523(7561);455-458
[PubMed:26087396] (I p)

Shzeena Dad, Nanna D Rendtorff, Erik Kann, Anders Albrechtsen, Mana M Mehrjouy, Mads Bak, Niels Tommerup, Lisbeth Tranebjærg, Thomas Rosenberg, Hanne Jensen, Lisbeth B Møller
Partial USH2A deletions contribute to Usher syndrome in Denmark.
Eur. J. Hum. Genet.: 2015, 23(12);1646-51
[PubMed:25804404] (I p)

Ida Moltke, Matteo Fumagalli, Thorfinn S Korneliussen, Jacob E Crawford, Peter Bjerregaard, Marit E Jørgensen, Niels Grarup, Hans Christian Gulløv, Allan Linneberg, Oluf Pedersen, Torben Hansen, Rasmus Nielsen, Anders Albrechtsen
Uncovering the genetic history of the present-day Greenlandic population.
Am. J. Hum. Genet.: 2015, 96(1);54-69
[PubMed:25557782] (I p)

Rute R da Fonseca, Bruce D Smith, Nathan Wales, Enrico Cappellini, Pontus Skoglund, Matteo Fumagalli, José Alfredo Samaniego, Christian Carøe, María C Ávila-Arcos, David E Hufnagel, Thorfinn Sand Korneliussen, Filipe Garrett Vieira, Mattias Jakobsson, Bernardo Arriaza, Eske Willerslev, Rasmus Nielsen, Matthew B Hufford, Anders Albrechtsen, Jeffrey Ross-Ibarra, M Thomas P Gilbert
The origin and evolution of maize in the Southwestern United States.
Nat Plants: 2015, 1;14003
[PubMed:27246050] (I e)

Julie H Laursen, Helle Bach Søndergaard, Anders Albrechtsen, Ruth Frikke-Schmidt, Nils Koch-Henriksen, Per Soelberg Sørensen, Finn Sellebjerg, Annette Oturai
Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.
Mult. Scler.: 2015, 21(11);1414-22
[PubMed:25533295] (I p)

Mikkel Schubert, Hákon Jónsson, Dan Chang, Clio Der Sarkissian, Luca Ermini, Aurélien Ginolhac, Anders Albrechtsen, Isabelle Dupanloup, Adrien Foucal, Bent Petersen, Matteo Fumagalli, Maanasa Raghavan, Andaine Seguin-Orlando, Thorfinn S Korneliussen, Amhed M V Velazquez, Jesper Stenderup, Cindi A Hoover, Carl-Johan Rubin, Ahmed H Alfarhan, Saleh A Alquraishi, Khaled A S Al-Rasheid, David E MacHugh, Ted Kalbfleisch, James N MacLeod, Edward M Rubin, Thomas Sicheritz-Ponten, Leif Andersson, Michael Hofreiter, Tomas Marques-Bonet, M Thomas P Gilbert, Rasmus Nielsen, Laurent Excoffier, Eske Willerslev, Beth Shapiro, Ludovic Orlando
Prehistoric genomes reveal the genetic foundation and cost of horse domestication.
Proc. Natl. Acad. Sci. U.S.A.: 2014, 111(52);E5661-9
[PubMed:25512547] (I p)

Anna-Sapfo Malaspinas, Oscar Lao, Hannes Schroeder, Morten Rasmussen, Maanasa Raghavan, Ida Moltke, Paula F Campos, Francisca Santana Sagredo, Simon Rasmussen, Vanessa F Gonçalves, Anders Albrechtsen, Morten E Allentoft, Philip L F Johnson, Mingkun Li, Silvia Reis, Danilo V Bernardo, Michael DeGiorgio, Ana T Duggan, Murilo Bastos, Yong Wang, Jesper Stenderup, J Victor Moreno-Mayar, Søren Brunak, Thomas Sicheritz-Ponten, Emily Hodges, Gregory J Hannon, Ludovic Orlando, T Douglas Price, Jeffrey D Jensen, Rasmus Nielsen, Jan Heinemeier, Jesper Olsen, Claudia Rodrigues-Carvalho, Marta Mirazón Lahr, Walter A Neves, Manfred Kayser, Thomas Higham, Mark Stoneking, Sergio D J Pena, Eske Willerslev
Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil.
Curr. Biol.: 2014, 24(21);R1035-7
[PubMed:25455029] (I p)

Hákon Jónsson, Mikkel Schubert, Andaine Seguin-Orlando, Aurélien Ginolhac, Lillian Petersen, Matteo Fumagalli, Anders Albrechtsen, Bent Petersen, Thorfinn S Korneliussen, Julia T Vilstrup, Teri Lear, Jennifer Leigh Myka, Judith Lundquist, Donald C Miller, Ahmed H Alfarhan, Saleh A Alquraishi, Khaled A S Al-Rasheid, Julia Stagegaard, Günter Strauss, Mads Frost Bertelsen, Thomas Sicheritz-Ponten, Douglas F Antczak, Ernest Bailey, Rasmus Nielsen, Eske Willerslev, Ludovic Orlando
Speciation with gene flow in equids despite extensive chromosomal plasticity.
Proc. Natl. Acad. Sci. U.S.A.: 2014, 111(52);18655-60
[PubMed:25453089] (I p)

Thorfinn Sand Korneliussen, Anders Albrechtsen, Rasmus Nielsen
ANGSD: Analysis of Next Generation Sequencing Data.
BMC Bioinformatics: 2014, 15;356
[PubMed:25420514] (I e)

Andaine Seguin-Orlando, Thorfinn S Korneliussen, Martin Sikora, Anna-Sapfo Malaspinas, Andrea Manica, Ida Moltke, Anders Albrechtsen, Amy Ko, Ashot Margaryan, Vyacheslav Moiseyev, Ted Goebel, Michael Westaway, David Lambert, Valeri Khartanovich, Jeffrey D Wall, Philip R Nigst, Robert A Foley, Marta Mirazon Lahr, Rasmus Nielsen, Ludovic Orlando, Eske Willerslev
Paleogenomics. Genomic structure in Europeans dating back at least 36,200 years.
Science: 2014, 346(6213);1113-8
[PubMed:25378462] (I p)

Maanasa Raghavan, Michael DeGiorgio, Anders Albrechtsen, Ida Moltke, Pontus Skoglund, Thorfinn S Korneliussen, Bjarne Grønnow, Martin Appelt, Hans Christian Gulløv, T Max Friesen, William Fitzhugh, Helena Malmström, Simon Rasmussen, Jesper Olsen, Linea Melchior, Benjamin T Fuller, Simon M Fahrni, Thomas Stafford, Vaughan Grimes, M A Priscilla Renouf, Jerome Cybulski, Niels Lynnerup, Marta Mirazon Lahr, Kate Britton, Rick Knecht, Jette Arneborg, Mait Metspalu, Omar E Cornejo, Anna-Sapfo Malaspinas, Yong Wang, Morten Rasmussen, Vibha Raghavan, Thomas V O Hansen, Elza Khusnutdinova, Tracey Pierre, Kirill Dneprovsky, Claus Andreasen, Hans Lange, M Geoffrey Hayes, Joan Coltrain, Victor A Spitsyn, Anders Götherström, Ludovic Orlando, Toomas Kivisild, Richard Villems, Michael H Crawford, Finn C Nielsen, Jørgen Dissing, Jan Heinemeier, Morten Meldgaard, Carlos Bustamante, Dennis H O'Rourke, Mattias Jakobsson, M Thomas P Gilbert, Rasmus Nielsen, Eske Willerslev
The genetic prehistory of the New World Arctic.
Science: 2014, 345(6200);1255832
[PubMed:25170159] (I p)

Ida Moltke, Niels Grarup, Marit E Jørgensen, Peter Bjerregaard, Jonas T Treebak, Matteo Fumagalli, Thorfinn S Korneliussen, Marianne A Andersen, Thomas S Nielsen, Nikolaj T Krarup, Anette P Gjesing, Juleen R Zierath, Allan Linneberg, Xueli Wu, Guangqing Sun, Xin Jin, Jumana Al-Aama, Jun Wang, Knut Borch-Johnsen, Oluf Pedersen, Rasmus Nielsen, Anders Albrechtsen, Torben Hansen
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.
Nature: 2014, 512(7513);190-3
[PubMed:25043022] (I p)

Morten Rasmussen, Sarah L Anzick, Michael R Waters, Pontus Skoglund, Michael DeGiorgio, Thomas W Stafford, Simon Rasmussen, Ida Moltke, Anders Albrechtsen, Shane M Doyle, G David Poznik, Valborg Gudmundsdottir, Rachita Yadav, Anna-Sapfo Malaspinas, Samuel Stockton White, Morten E Allentoft, Omar E Cornejo, Kristiina Tambets, Anders Eriksson, Peter D Heintzman, Monika Karmin, Thorfinn Sand Korneliussen, David J Meltzer, Tracey L Pierre, Jesper Stenderup, Lauri Saag, Vera M Warmuth, Margarida C Lopes, Ripan S Malhi, Søren Brunak, Thomas Sicheritz-Ponten, Ian Barnes, Matthew Collins, Ludovic Orlando, Francois Balloux, Andrea Manica, Ramneek Gupta, Mait Metspalu, Carlos D Bustamante, Mattias Jakobsson, Rasmus Nielsen, Eske Willerslev
The genome of a Late Pleistocene human from a Clovis burial site in western Montana.
Nature: 2014, 506(7487);225-9
[PubMed:24522598] (I p)

Shengting Li, Soren Besenbacher, Yingrui Li, Karsten Kristiansen, Niels Grarup, Anders Albrechtsen, Thomas Sparsø, Thorfinn Korneliussen, Torben Hansen, Jun Wang, Rasmus Nielsen, Oluf Pedersen, Lars Bolund, Mikkel H Schierup
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population.
Eur. J. Hum. Genet.: 2014, 22(8);1040-5
[PubMed:24448545] (I p)

Kirk E Lohmueller, Thomas Sparsø, Qibin Li, Ehm Andersson, Thorfinn Korneliussen, Anders Albrechtsen, Karina Banasik, Niels Grarup, Ingileif Hallgrimsdottir, Kristoffer Kiil, Tuomas O Kilpeläinen, Nikolaj T Krarup, Tune H Pers, Gaston Sanchez, Youna Hu, Michael Degiorgio, Torben Jørgensen, Annelli Sandbæk, Torsten Lauritzen, Søren Brunak, Karsten Kristiansen, Yingrui Li, Torben Hansen, Jun Wang, Rasmus Nielsen, Oluf Pedersen
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes.
Am. J. Hum. Genet.: 2013, 93(6);1072-86
[PubMed:24290377] (I p)

Maanasa Raghavan, Pontus Skoglund, Kelly E Graf, Mait Metspalu, Anders Albrechtsen, Ida Moltke, Simon Rasmussen, Thomas W Stafford, Ludovic Orlando, Ene Metspalu, Monika Karmin, Kristiina Tambets, Siiri Rootsi, Reedik Mägi, Paula F Campos, Elena Balanovska, Oleg Balanovsky, Elza Khusnutdinova, Sergey Litvinov, Ludmila P Osipova, Sardana A Fedorova, Mikhail I Voevoda, Michael DeGiorgio, Thomas Sicheritz-Ponten, Søren Brunak, Svetlana Demeshchenko, Toomas Kivisild, Richard Villems, Rasmus Nielsen, Mattias Jakobsson, Eske Willerslev
Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans.
Nature: 2014, 505(7481);87-91
[PubMed:24256729] (I p)

Ida Moltke, Anders Albrechtsen
RelateAdmix: a software tool for estimating relatedness between admixed individuals.
Bioinformatics: 2014, 30(7);1027-8
[PubMed:24215025] (I p)

Thorfinn Sand Korneliussen, Ida Moltke, Anders Albrechtsen, Rasmus Nielsen
Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data.
BMC Bioinformatics: 2013, 14;289
[PubMed:24088262] (I e)

Line Skotte, Thorfinn Sand Korneliussen, Anders Albrechtsen
Estimating individual admixture proportions from next generation sequencing data.
Genetics: 2013, 195(3);693-702
[PubMed:24026093] (I p)

Matteo Fumagalli, Filipe G Vieira, Thorfinn Sand Korneliussen, Tyler Linderoth, Emilia Huerta-Sánchez, Anders Albrechtsen, Rasmus Nielsen
Quantifying population genetic differentiation from next-generation sequencing data.
Genetics: 2013, 195(3);979-92
[PubMed:23979584] (I p)

Filipe G Vieira, Matteo Fumagalli, Anders Albrechtsen, Rasmus Nielsen
Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation.
Genome Res.: 2013, 23(11);1852-61
[PubMed:23950147] (I p)

Margit Hørup Larsen, Anders Albrechtsen, Lise Wegner Thørner, Thomas Werge, Thomas Hansen, Ulrik Gether, Eva Haastrup, Henrik Ullum
Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort.
PLoS ONE: 2013, 8(6);e66262
[PubMed:23823136] (I e)

Ludovic Orlando, Aurélien Ginolhac, Guojie Zhang, Duane Froese, Anders Albrechtsen, Mathias Stiller, Mikkel Schubert, Enrico Cappellini, Bent Petersen, Ida Moltke, Philip L F Johnson, Matteo Fumagalli, Julia T Vilstrup, Maanasa Raghavan, Thorfinn Korneliussen, Anna-Sapfo Malaspinas, Josef Vogt, Damian Szklarczyk, Christian D Kelstrup, Jakob Vinther, Andrei Dolocan, Jesper Stenderup, Amhed M V Velazquez, James Cahill, Morten Rasmussen, Xiaoli Wang, Jiumeng Min, Grant D Zazula, Andaine Seguin-Orlando, Cecilie Mortensen, Kim Magnussen, John F Thompson, Jacobo Weinstock, Kristian Gregersen, Knut H Røed, Véra Eisenmann, Carl J Rubin, Donald C Miller, Douglas F Antczak, Mads F Bertelsen, Søren Brunak, Khaled A S Al-Rasheid, Oliver Ryder, Leif Andersson, John Mundy, Anders Krogh, M Thomas P Gilbert, Kurt Kjær, Thomas Sicheritz-Ponten, Lars Juhl Jensen, Jesper V Olsen, Michael Hofreiter, Rasmus Nielsen, Beth Shapiro, Jun Wang, Eske Willerslev
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse.
Nature: 2013, 499(7456);74-8
[PubMed:23803765] (I p)

Niels Grarup, Patrick Sulem, Camilla H Sandholt, Gudmar Thorleifsson, Tarunveer S Ahluwalia, Valgerdur Steinthorsdottir, Helgi Bjarnason, Daniel F Gudbjartsson, Olafur T Magnusson, Thomas Sparsø, Anders Albrechtsen, Augustine Kong, Gisli Masson, Geng Tian, Hongzhi Cao, Chao Nie, Karsten Kristiansen, Lise Lotte Husemoen, Betina Thuesen, Yingrui Li, Rasmus Nielsen, Allan Linneberg, Isleifur Olafsson, Gudmundur I Eyjolfsson, Torben Jørgensen, Jun Wang, Torben Hansen, Unnur Thorsteinsdottir, Kari Stefánsson, Oluf Pedersen
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets.
PLoS Genet.: 2013, 9(6);e1003530
[PubMed:23754956] (I p)

A Albrechtsen, N Grarup, Y Li, T Sparsø, G Tian, H Cao, T Jiang, S Y Kim, T Korneliussen, Q Li, C Nie, R Wu, L Skotte, A P Morris, C Ladenvall, S Cauchi, A Stančáková, G Andersen, A Astrup, K Banasik, A J Bennett, L Bolund, G Charpentier, Y Chen, J M Dekker, A S F Doney, M Dorkhan, T Forsen, T M Frayling, C J Groves, Y Gui, G Hallmans, A T Hattersley, K He, G A Hitman, J Holmkvist, S Huang, H Jiang, X Jin, J M Justesen, K Kristiansen, J Kuusisto, M Lajer, O Lantieri, W Li, H Liang, Q Liao, X Liu, T Ma, X Ma, M P Manijak, M Marre, J Mokrosiński, A D Morris, B Mu, A A Nielsen, G Nijpels, P Nilsson, C N A Palmer, N W Rayner, F Renström, R Ribel-Madsen, N Robertson, O Rolandsson, P Rossing, T W Schwartz, D.E.S.I.R. Study Group, P E Slagboom, M Sterner, DIAGRAM Consortium, M Tang, L Tarnow, T Tuomi, E van't Riet, N van Leeuwen, T V Varga, M A Vestmar, M Walker, B Wang, Y Wang, H Wu, F Xi, L Yengo, C Yu, X Zhang, J Zhang, Q Zhang, W Zhang, H Zheng, Y Zhou, D Altshuler, L M 't Hart, P W Franks, B Balkau, P Froguel, M I McCarthy, M Laakso, L Groop, C Christensen, I Brandslund, T Lauritzen, D R Witte, A Linneberg, T Jørgensen, T Hansen, J Wang, R Nielsen, O Pedersen
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.
Diabetologia: 2013, 56(2);298-310
[PubMed:23160641] (I p)

Rasmus Nielsen, Thorfinn Korneliussen, Anders Albrechtsen, Yingrui Li, Jun Wang
SNP calling, genotype calling, and sample allele frequency estimation from New-Generation Sequencing data.
PLoS ONE: 2012, 7(7);e37558
[PubMed:22911679] (I p)

Line Skotte, Thorfinn Sand Korneliussen, Anders Albrechtsen
Association testing for next-generation sequencing data using score statistics.
Genet. Epidemiol.: 2012, 36(5);430-7
[PubMed:22570057] (I p)

Kirk E Lohmueller, Anders Albrechtsen, Yingrui Li, Su Yeon Kim, Thorfinn Korneliussen, Nicolas Vinckenbosch, Geng Tian, Emilia Huerta-Sanchez, Alison F Feder, Niels Grarup, Torben Jørgensen, Tao Jiang, Daniel R Witte, Annelli Sandbæk, Ines Hellmann, Torsten Lauritzen, Torben Hansen, Oluf Pedersen, Jun Wang, Rasmus Nielsen
Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.
PLoS Genet.: 2011, 7(10);e1002326
[PubMed:22022285] (I p)

Morten Rasmussen, Xiaosen Guo, Yong Wang, Kirk E Lohmueller, Simon Rasmussen, Anders Albrechtsen, Line Skotte, Stinus Lindgreen, Mait Metspalu, Thibaut Jombart, Toomas Kivisild, Weiwei Zhai, Anders Eriksson, Andrea Manica, Ludovic Orlando, Francisco M De La Vega, Silvana Tridico, Ene Metspalu, Kasper Nielsen, María C Ávila-Arcos, J Víctor Moreno-Mayar, Craig Muller, Joe Dortch, M Thomas P Gilbert, Ole Lund, Agata Wesolowska, Monika Karmin, Lucy A Weinert, Bo Wang, Jun Li, Shuaishuai Tai, Fei Xiao, Tsunehiko Hanihara, George van Driem, Aashish R Jha, François-Xavier Ricaut, Peter de Knijff, Andrea B Migliano, Irene Gallego Romero, Karsten Kristiansen, David M Lambert, Søren Brunak, Peter Forster, Bernd Brinkmann, Olaf Nehlich, Michael Bunce, Michael Richards, Ramneek Gupta, Carlos D Bustamante, Anders Krogh, Robert A Foley, Marta M Lahr, Francois Balloux, Thomas Sicheritz-Pontén, Richard Villems, Rasmus Nielsen, Jun Wang, Eske Willerslev
An Aboriginal Australian genome reveals separate human dispersals into Asia.
Science: 2011, 334(6052);94-8
[PubMed:21940856] (I p)

Su Yeon Kim, Kirk E Lohmueller, Anders Albrechtsen, Yingrui Li, Thorfinn Korneliussen, Geng Tian, Niels Grarup, Tao Jiang, Gitte Andersen, Daniel Witte, Torben Jorgensen, Torben Hansen, Oluf Pedersen, Jun Wang, Rasmus Nielsen
Estimation of allele frequency and association mapping using next-generation sequencing data.
BMC Bioinformatics: 2011, 12;231
[PubMed:21663684] (I e)

Rasmus Nielsen, Joshua S Paul, Anders Albrechtsen, Yun S Song
Genotype and SNP calling from next-generation sequencing data.
Nat. Rev. Genet.: 2011, 12(6);443-51
[PubMed:21587300] (I p)

Ida Moltke, Anders Albrechtsen, Thomas V O Hansen, Finn C Nielsen, Rasmus Nielsen
A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics.
Genome Res.: 2011, 21(7);1168-80
[PubMed:21493780] (I p)

Yingrui Li, Nicolas Vinckenbosch, Geng Tian, Emilia Huerta-Sanchez, Tao Jiang, Hui Jiang, Anders Albrechtsen, Gitte Andersen, Hongzhi Cao, Thorfinn Korneliussen, Niels Grarup, Yiran Guo, Ines Hellman, Xin Jin, Qibin Li, Jiangtao Liu, Xiao Liu, Thomas Sparsø, Meifang Tang, Honglong Wu, Renhua Wu, Chang Yu, Hancheng Zheng, Arne Astrup, Lars Bolund, Johan Holmkvist, Torben Jørgensen, Karsten Kristiansen, Ole Schmitz, Thue W Schwartz, Xiuqing Zhang, Ruiqiang Li, Huanming Yang, Jian Wang, Torben Hansen, Oluf Pedersen, Rasmus Nielsen, Jun Wang
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.
Nat. Genet.: 2010, 42(11);969-72
[PubMed:20890277] (I p)

Anders Albrechtsen, Ida Moltke, Rasmus Nielsen
Natural selection and the distribution of identity-by-descent in the human genome.
Genetics: 2010, 186(1);295-308
[PubMed:20592267] (I p)

Anders Albrechtsen, Finn Cilius Nielsen, Rasmus Nielsen
Ascertainment biases in SNP chips affect measures of population divergence.
Mol. Biol. Evol.: 2010, 27(11);2534-47
[PubMed:20558595] (I p)

Thomas V O Hansen, Lars Jønson, Anders Albrechtsen, Ane Y Steffensen, Eva Bergsten, Torben Myrhøj, Bent Ejlertsen, Finn C Nielsen
Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer.
Breast Cancer Res. Treat.: 2010, 124(1);259-64
[PubMed:20437199] (I p)

Anette P Gjesing, Lesli H Larsen, Signe S Torekov, Irena Aldhoon Hainerová, Rahul Kapur, Anders Johansen, Anders Albrechtsen, Sylvia Boj, Birgitte Holst, Angela Harper, Søren A Urhammer, Knut Borch-Johnsen, Charlotta Pisinger, Søren M Echwald, Hans Eiberg, Arne Astrup, Jan Lebl, Jorge Ferrer, Thue W Schwartz, Torben Hansen, Oluf Pedersen
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity.
PLoS ONE: 2010, 5(4);e10084
[PubMed:20404923] (I e)

Morten Rasmussen, Yingrui Li, Stinus Lindgreen, Jakob Skou Pedersen, Anders Albrechtsen, Ida Moltke, Mait Metspalu, Ene Metspalu, Toomas Kivisild, Ramneek Gupta, Marcelo Bertalan, Kasper Nielsen, M Thomas P Gilbert, Yong Wang, Maanasa Raghavan, Paula F Campos, Hanne Munkholm Kamp, Andrew S Wilson, Andrew Gledhill, Silvana Tridico, Michael Bunce, Eline D Lorenzen, Jonas Binladen, Xiaosen Guo, Jing Zhao, Xiuqing Zhang, Hao Zhang, Zhuo Li, Minfeng Chen, Ludovic Orlando, Karsten Kristiansen, Mads Bak, Niels Tommerup, Christian Bendixen, Tracey L Pierre, Bjarne Grønnow, Morten Meldgaard, Claus Andreasen, Sardana A Fedorova, Ludmila P Osipova, Thomas F G Higham, Christopher Bronk Ramsey, Thomas V O Hansen, Finn C Nielsen, Michael H Crawford, Søren Brunak, Thomas Sicheritz-Pontén, Richard Villems, Rasmus Nielsen, Anders Krogh, Jun Wang, Eske Willerslev
Ancient human genome sequence of an extinct Palaeo-Eskimo.
Nature: 2010, 463(7282);757-62
[PubMed:20148029] (I p)

Camilla Helene Sandholt, Thomas Sparsø, Niels Grarup, Anders Albrechtsen, Katrine Almind, Lars Hansen, Ulla Toft, Torben Jørgensen, Torben Hansen, Oluf Pedersen
Combined analyses of 20 common obesity susceptibility variants.
Diabetes: 2010, 59(7);1667-73
[PubMed:20110568] (I p)

E Axelsson, A Albrechtsen, A P van, L Li, H J Megens, A L J Vereijken, R P M A Crooijmans, M A M Groenen, H Ellegren, E Willerslev, R Nielsen
Segregation distortion in chicken and the evolutionary consequences of female meiotic drive in birds.
Heredity (Edinb): 2010, 105(3);290-8
[PubMed:20104236] (I p)

K Fosgerau, P Galle, T Hansen, A Albrechtsen, C de Lemos Rieper, B Klarlund Pedersen, L Kongskov Larsen, A Randrup Thomsen, O Pedersen, M Bagge Hansen, A Steensberg
Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes.
J. Endocrinol.: 2010, 204(3);265-73
[PubMed:20016056] (I p)

Johan Rung, Stéphane Cauchi, Anders Albrechtsen, Lishuang Shen, Ghislain Rocheleau, Christine Cavalcanti-Proença, François Bacot, Beverley Balkau, Alexandre Belisle, Knut Borch-Johnsen, Guillaume Charpentier, Christian Dina, Emmanuelle Durand, Paul Elliott, Samy Hadjadj, Marjo-Riitta Järvelin, Jaana Laitinen, Torsten Lauritzen, Michel Marre, Alexander Mazur, David Meyre, Alexandre Montpetit, Charlotta Pisinger, Barry Posner, Pernille Poulsen, Anneli Pouta, Marc Prentki, Rasmus Ribel-Madsen, Aimo Ruokonen, Anelli Sandbaek, David Serre, Jean Tichet, Martine Vaxillaire, Jørgen F P Wojtaszewski, Allan Vaag, Torben Hansen, Constantin Polychronakos, Oluf Pedersen, Philippe Froguel, Robert Sladek
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.
Nat. Genet.: 2009, 41(10);1110-5
[PubMed:19734900] (I p)

C S Rose, N Grarup, N T Krarup, P Poulsen, L Wegner, T Nielsen, K Banasik, K Faerch, G Andersen, A Albrechtsen, K Borch-Johnsen, J O Clausen, T Jørgensen, A Vaag, O Pedersen, T Hansen
A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads.
Diabetologia: 2009, 52(10);2122-9
[PubMed:19669124] (I p)

Tune H Pers, Anders Albrechtsen, Claus Holst, Thorkild I A Sørensen, Thomas A Gerds
The validation and assessment of machine learning: a game of prediction from high-dimensional data.
PLoS ONE: 2009, 4(8);e6287
[PubMed:19652722] (I e)

T Sparsø, N Grarup, C Andreasen, A Albrechtsen, J Holmkvist, G Andersen, T Jørgensen, K Borch-Johnsen, A Sandbaek, T Lauritzen, S Madsbad, T Hansen, O Pedersen
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Diabetologia: 2009, 52(7);1308-14
[PubMed:19404609] (I p)

Rasmus Nielsen, Melissa J Hubisz, Ines Hellmann, Dara Torgerson, Aida M Andrés, Anders Albrechtsen, Ryan Gutenkunst, Mark D Adams, Michele Cargill, Adam Boyko, Amit Indap, Carlos D Bustamante, Andrew G Clark
Darwinian and demographic forces affecting human protein coding genes.
Genome Res.: 2009, 19(5);838-49
[PubMed:19279335] (P p)

T Gylvin, J Ek, R Nolsøe, A Albrechtsen, G Andersen, R Bergholdt, C Brorsson, C H Bang-Berthelsen, T Hansen, A E Karlsen, N Billestrup, K Borch-Johnsen, T Jørgensen, O Pedersen, T Mandrup-Poulsen, J Nerup, F Pociot
Functional SOCS1 polymorphisms are associated with variation in obesity in whites.
Diabetes Obes Metab: 2009, 11(3);196-203
[PubMed:19215277] (I p)

Anders Albrechtsen, Thorfinn Sand Korneliussen, Ida Moltke, Thomas van Overseem Hansen, Finn Cilius Nielsen, Rasmus Nielsen
Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium.
Genet. Epidemiol.: 2009, 33(3);266-74
[PubMed:19025785] (I p)

Thomas V O Hansen, Marie Luise Bisgaard, Lars Jønson, Anders Albrechtsen, Bettina Filtenborg-Barnkob, Hans Eiberg, Bent Ejlertsen, Finn C Nielsen
Novel de novo BRCA2 mutation in a patient with a family history of breast cancer.
BMC Med. Genet.: 2008, 9;58
[PubMed:18597679] (I e)

T Sparsø, G Andersen, A Albrechtsen, T Jørgensen, K Borch-Johnsen, A Sandbaek, T Lauritzen, J Wasson, M A Permutt, B Glaser, S Madsbad, O Pedersen, T Hansen
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Diabetologia: 2008, 51(9);1646-52
[PubMed:18568334] (P p)

Niels Grarup, Gitte Andersen, Nikolaj T Krarup, Anders Albrechtsen, Ole Schmitz, Torben Jørgensen, Knut Borch-Johnsen, Torben Hansen, Oluf Pedersen
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Diabetes: 2008, 57(9);2534-40
[PubMed:18567820] (I p)

Thomas v O Hansen, Lars Jønson, Anders Albrechtsen, Mette K Andersen, Bent Ejlertsen, Finn C Nielsen
Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families.
Breast Cancer Res. Treat.: 2009, 115(2);315-23
[PubMed:18546071] (I p)

Thomas V O Hansen, Bent Ejlertsen, Anders Albrechtsen, Eva Bergsten, Peter Bjerregaard, Torben Hansen, Torben Myrhøj, Peter B Nielsen, Vera Timmermans-Wielenga, Mette K Andersen, Lars Jønson, Finn C Nielsen
A common Greenlandic Inuit BRCA1 RING domain founder mutation.
Breast Cancer Res. Treat.: 2009, 115(1);69-76
[PubMed:18500671] (I p)

Niels Grarup, Camilla H Andreasen, Mette K Andersen, Anders Albrechtsen, Annelli Sandbaek, Torsten Lauritzen, Knut Borch-Johnsen, Torben Jørgensen, Ole Schmitz, Torben Hansen, Oluf Pedersen
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.
J. Clin. Endocrinol. Metab.: 2008, 93(6);2294-9
[PubMed:18364377] (P p)

T Sparsø, G Andersen, T Nielsen, K S Burgdorf, A P Gjesing, A L Nielsen, A Albrechtsen, S S Rasmussen, T Jørgensen, K Borch-Johnsen, A Sandbaek, T Lauritzen, S Madsbad, T Hansen, O Pedersen
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Diabetologia: 2008, 51(1);70-5
[PubMed:18008060] (P p)

Camilla H Andreasen, Kirstine L Stender-Petersen, Mette S Mogensen, Signe S Torekov, Lise Wegner, Gitte Andersen, Arne L Nielsen, Anders Albrechtsen, Knut Borch-Johnsen, Signe S Rasmussen, Jesper O Clausen, Annelli Sandbaek, Torsten Lauritzen, Lars Hansen, Torben Jørgensen, Oluf Pedersen, Torben Hansen
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.
Diabetes: 2008, 57(1);95-101
[PubMed:17942823] (I p)

Niels Grarup, Chrisian S Rose, Ehm A Andersson, Gitte Andersen, Arne L Nielsen, Anders Albrechtsen, Jesper O Clausen, Signe S Rasmussen, Torben Jørgensen, Annelli Sandbaek, Torsten Lauritzen, Ole Schmitz, Torben Hansen, Oluf Pedersen
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Diabetes: 2007, 56(12);3105-11
[PubMed:17827400] (I p)

T W Boesgaard, S I Castella, G Andersen, A Albrechtsen, T Sparsø, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.
Diabet. Med.: 2007, 24(7);702-6
[PubMed:17459095] (P p)

Anders Albrechtsen, Sofie Castella, Gitte Andersen, Torben Hansen, Oluf Pedersen, Rasmus Nielsen
A Bayesian multilocus association method: allowing for higher-order interaction in association studies.
Genetics: 2007, 176(2);1197-208
[PubMed:17435250] (P p)

N Grarup, A Albrechtsen, J Ek, K Borch-Johnsen, T Jørgensen, O Schmitz, T Hansen, O Pedersen
Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people.
Diabetologia: 2007, 50(6);1201-8
[PubMed:17431579] (P p)

A P Gjesing, G Andersen, A Albrechtsen, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.
Diabet. Med.: 2007, 24(4);392-7
[PubMed:17335470] (P p)

Niels Grarup, Mette K Andersen, Camilla H Andreasen, Anders Albrechtsen, Knut Borch-Johnsen, Torben Jørgensen, Johan Auwerx, Ole Schmitz, Torben Hansen, Oluf Pedersen
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.
J. Clin. Endocrinol. Metab.: 2007, 92(1);363-6
[PubMed:17077128] (P p)

S S Torekov, L H Larsen, G Andersen, A Albrechtsen, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects.
Diabetologia: 2006, 49(11);2653-8
[PubMed:17019604] (P p)

L Wegner, G Andersen, A Albrechtsen, T Sparsø, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes.
Diabet. Med.: 2006, 23(10);1140-4
[PubMed:16978381] (P p)

N Grarup, S A Urhammer, J Ek, A Albrechtsen, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.
Diabetologia: 2006, 49(9);2097-104
[PubMed:16865358] (P p)

L H Larsen, C S Rose, T Sparsø, J Overgaard, S S Torekov, N Grarup, D P Jensen, A Albrechtsen, G Andersen, J Ek, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.
Int J Obes (Lond): 2007, 31(2);365-70
[PubMed:16755280] (P p)

Jakob Ek, Sara P Hansen, Maria Lajer, Carine Nicot, Trine W Boesgaard, Stepanka Pruhova, Anders Johansen, Anders Albrechtsen, Knud Yderstraede, Jeannet Lauenborg, Marcelina Parrizas, Sylvia F Boj, Torben Jørgensen, Knut Borch-Johnsen, Peter Damm, Jorge Ferrer, Jan Lebl, Oluf Pedersen, Torben Hansen
A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes.
Diabetes: 2006, 55(6);1869-73
[PubMed:16731855] (P p)

G Andersen, J Overgaard, A Albrechtsen, C Glümer, K Borch-Johnsen, T Jørgensen, T Hansen, O Pedersen
Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.
Diabetologia: 2006, 49(1);75-82
[PubMed:16284746] (P p)