Albrecht: Created page with "==Estimator from genotype probabilities== If the genotype probabilities are known the frequencies can be estimated by summing up the posterior probabilities $p(G=g|D)$
2014-02-26T15:44:28Z

Created page with "==Estimator from genotype probabilities== If the genotype probabilities are known the frequencies can be estimated by summing up the posterior probabilities <math> p(G=g|D)</..."

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==Estimator from genotype probabilities==

If the genotype probabilities are known the frequencies can be estimated by summing up the posterior probabilities <math> p(G=g|D)</math> where <math>D</math> is the sequencing data and <math>g\in\{0,1,2\}</math> the allele count of the minor allele. The frequency estimate

<math>
\hat{f}=\frac{1}{2N}\sum_i^N \left(2p(G=2|D)+p(G=1|D)\right)
</math>

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