ANGSD: Analysis of next generation Sequencing Data

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Genotype Likelihoods: Difference between revisions

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===soapSNP===
===soapSNP===
-GL 3
-GL 3
Thorfinn could not make it work
Anders destroyed an otherwise well working estimator
 
===Kim et al.===
===Kim et al.===
-GL 4
-GL 4
Thorfinn could not make it work
Thorfinn could not make it work
[[Kim10|Citation]] [[Kim11|Citation]]
[[Kim10|Citation]] [[Kim11|Citation]]

Revision as of 16:02, 22 June 2012

Analysis from sequencing data

<classdiagram> // [input|bam files;SOAP files{bg:orange}]->[sequence data]

[sequence data]->[genotype likelihoods|samtools;GATK;soapSNP;kim et.al]
</classdiagram>

Genotype likelihoods from alignments

-GL [int]

If your input is sequencing file you can estimate genotype likelhoods from the mapped reads. Four different methods are available.

Samtools

-GL 1

This methods has a random component. To get the exact same results as samtools use nThreads=1.

GATK

-GL 2

soapSNP

-GL 3 Anders destroyed an otherwise well working estimator

Kim et al.

-GL 4 Thorfinn could not make it work Citation Citation